Daniil Medvedev  The second seed was knocked in the first round against Brazil’s Thiago Seyboth Wild

Jessica Pegula  The world number 3 lost in straight sets against Belgium’s Elise Mertens in the third round

Caroline Garcia  The 5th seed succumbed to a 6-4, 3-6, 5-7 loss against Anna Blinkova in the second round

Jannik Sinner  World number 9 Jannik Sinner was shocked by Daniel Altmaier in a match that went on for 5 hours and 26 minutes

Andrey Rublev  World number 7 Andrey Rublev was eliminated in the third round after losing against Lorenzo Sonego

Maria Sakkari  The world number 8 suffered a defeat at the hands of World No. 43 Karolina Muchova in the first round

Carlos Alcaraz to play Novak Djokovic in French Open semi-finals